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Monday, June 9, 2008

Super Biochemistry--unit 101-150

101: Helper T Cell Action.

102: Variations on a Theme.

103: Coreceptor CD4.

104: Class II MHC Protein.

105: Presentation of Peptides from Internalized Proteins.

106: Consequences of Cytotoxic-T-Cell Action.

107: T-Cell Activation.

108: T-Cell Receptor Complex.

109: The Coreceptor CD8.

110: T-Cell Receptor Class I MHC Complex.

111: T-Cell Receptor.

112: Anchor Residues.

113: Class I MHC Peptide-Binding Site.

114: Class I MHC Protein.

115: Presentation of Peptides from Cytosolic Proteins.

116: Intracellular Pathogen.

RNA Synthesis and Splicing

117: The Discovery of Catalytic RNA Was Revealing in Regard to Both Mechanism and Evolution

118: Complex Formed by TATA-Box-Binding Protein and DNA.

119: Transcription Initiation.

120: CAAT Box and GC Box.

121: TATA Box.

122: RNA Polymerase Poison.

123: Eukaryotic RNA polymerases

124: Transcription and Translation.

125: Transcription Is Catalyzed by RNA Polymerase

126: Antibiotic Action.

127: Primary Transcript.

128: Mechanism For the Termination of Transcription by Rho Protein.

129: Effect of Rho Protein On the Size of RNA Transcripts.

130: Termination Signal.

131: RNA-DNA Hybrid Separation.

132: Transcription Bubble.

133: DNA Unwinding.

134: Alternative Promoter Sequences.

135: Structure of the Sigma Subunit.

136: Prokaryotic Promoter Sequences.

137: Footprinting.

138: RNA Polymerase Active Site.

139: Subunits of RNA polymerase from E. coli

140: RNA synthesis is a key step in the expression of genetic information.

141: RNA Polymerase Structures.

142: An Overview of RNA Synthesis

143: RNA Synthesis and Splicing

144: Problems

145: Summary

146: Comparison of Splicing Pathways.

147: Self-Splicing Mechanism.

148: Structure of a Self-Splicing Intron.

149: Self-Splicing.

150: The Transcription Products of All Three Eukaryotic Polymerases Are Processed

Super Biochemistry--unit 151-200

151: Selected proteins exhibiting alternative RNA splicing

152: Alternative Splicing Patterns.

153: Splicing Catalytic Center.

154: Spliceosome Assembly.

155: Small nuclear ribonucleoprotein particles (snRNPs) in the splicing of mRNA precursors

156: Splicing Branch Point.

157: Splicing Mechanism Used for mRNA Precursors.

158: Splicing Defects.

159: Splice Sites.

160: RNA Editing.

161: Polyadenylation of a Primary Transcript.

162: Capping the 5 End.

163: Transfer RNA Precursor Processing.

164: Eukaryotic Transcription and Translation Are Separated in Space and Time

165: Transcription-Factor-Binding Sites.

166: Assembly of the Initiation Complex.


The Control of Gene Expression

167: The Greater Complexity of Eukaryotic Genomes Requires Elaborate Mechanisms for Gene Regulation

168: An Experimental Demonstration of Enhancer Function.

169: Enhancer Binding Sites.

170: Gal4 Binding Sites.

171: Higher-Order Chromatin Structure.

172: Homologous Histones.

173: Nucleosome Core Particle.

174: Chromatin Structure.

175: Yeast Chromosomes.

176: Prokaryotic DNA-Binding Proteins Bind Specifically to Regulatory Sites in Operons

177: DNA Recognition Through Beta Strands.

178: Helix-Turn-Helix Motif.

179: Structure of a Dimer of CAP Bound to DNA.

180: Binding Site for Catabolite Activator Protein (CAP).

181: Binding-Site Distributions.

182: Induction of the LAC Operon.

183: Effects of IPTG On LAC Repressor Structure.

184: LAC Repressor-DNA Interactions.

185: Structure of the LAC Repressor.

186: The LAC Operator.

187: Operons.

188: Beta-Galactosidase Induction.

189: Following the Beta-Galactosidase Reaction.

190: Programming Gene Expression.

191: Highly expressed protein-encoding genes of the pancreas and liver (as percentage of total mRNA pool)

192: The Control of Gene Expression

193: Chapter Integration Problem

194: Problems

195: Summary

196: Gene Expression Can Be Controlled at Posttranscriptional Levels

197: The IRE-BP Is an Aconitase.

198: Transferrin-receptor mRNA.

199: Iron-Response Element.

200: Structure of Ferritin.